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Symbol Name ID |
Clcn3
chloride channel, voltage-sensitive 3 MGI:103555 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased susceptibility to pharmacologically induced seizures |
seizures |
tonic-clonic seizures |
abnormal microglial cell physiology |
abnormal nervous system morphology |
abnormal brain morphology |
decreased brain size |
enlarged lateral ventricles |
abnormal entorhinal cortex morphology |
abnormal hippocampus morphology |
abnormal hippocampus pyramidal cell morphology |
decreased hippocampus pyramidal cell number |
hippocampal neuron degeneration |
small hippocampus |
hippocampus atrophy |
decreased cerebral cortex pyramidal cell number |
abnormal astrocyte morphology |
astrocytosis |
gliosis |
loss of GABAergic neurons |
decreased retina photoreceptor cell number |
photoreceptor inner segment degeneration |
disorganized photoreceptor outer segment |
photoreceptor outer segment degeneration |
abnormal synaptic vesicle morphology |
abnormal nervous system physiology |
impaired synaptic plasticity |
abnormal excitatory postsynaptic currents |
abnormal excitatory postsynaptic potential |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||
| Clcn3tm1Lamb/Clcn3tm1Lamb | ||||||||||||||||||||||||||||||
| Clcn3tm1Suc/Clcn3tm1Suc | ||||||||||||||||||||||||||||||
| Clcn3tm1Tjj/Clcn3tm1Tjj | ||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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